Brian L Frost, PhD

Hello! I'm Brian Lance Frost, a postdoctoral scientist at the Rockefeller University's Laboratory of Sensory Neuroscience (principal investigator A. James Hudspeth). I study the mechanisms that underly the sense of hearing from theoretical and experimental perspectives. I am also an adjunct professor of mathematics at the Cooper Union and New York University. This site hosts posts about my current research, publications and will eventually include my personal projects.

Email: bfrost@rockefeller.edu
Doctoral Thesis: Available as a PDF.
Curriculum Vitae: Available as a PDF.

Rest in Peace A. James Hudspeth - August 20, 2025

After a long battle with brain cancer, Jim Hudspeth died in his home this past Saturday. This news is heartbreaking to everyone in the scientific community, and particularly us here in the Hudspeth lab. Jim was one of the greatest men I ever had the pleasure to interact with, and I feel blessed that I was able to work under him.

He was not only a brilliant man with extensive knowledge of the sciences and arts, but also a compassionate man with a passion for mentoring and educating the people he crossed paths with. It is hard to believe that this man, so much larger than life, is no longer with us in this world.

We love and miss you, Jim!

Appointment Update! NYU Adjuct Instructorship - Fall 2025

I am happy to announce that I will be working at New York University in the coming semester. As an adjunct instructor in the Courant school of mathematics, I will be teaching an undergraduate course in probability theory. This will be in conjunction with my adjunct instructorship at the Cooper Union, where I will be teaching an undergraduate course in vector calculus. I look forward to the coming semester!

Publication Alert! Lineal Motion in the OHC-DC Junction - March 3, 2025

The Hearing Research special edition containing work discussed at Mechanics of Hearing 2025 is out, and our work on 2-D Outer Hair Cell-Deiters Cell junction motion made it in! The paper is primarily about a model, backed by a few 2-D motion recordings made using the method from our 2023 JASA paper, in which the OHCs may drive motion along a straight line rather than a non-degenerate ellipse in the longitudinal-transverse plane. Read it here! Or download as a PDF.

Publication Alert! Multi-Author OCT Review Article - December 4, 2024

A new, large multi-author paper was released yesterday covering various applications of OCT to cochlear micromechanics. Yours truly is an author of section 2.5, "Two issues arising from the uni-directional optical axis, and how to account for them." I am very happy that my work was considered substantial enough to merit inclusion in this publication! Read it here! Or download as a PDF.

New Site Launch - October 1, 2024

I've moved my site over from one hosted on Wix, a website-building and hosting platform, to one (very obviously) created by myself. The 1990s web vibe is an aesthetic choice, I promise! My apologies for the lack of content as I continue to build up the site.